PRMT5 and neoplasm: Furthermore, inhibition of KLF5 by mifepristone and its derivatives 22-24, metformin 25, mithramycin A 26, super-enhancer inhibitors 27, and the protein arginine N-methyltransferase 5 (PRMT5) inhibitor, PJ-68 28, suppress BLBC stemness and tumor growth.