To further verify the pro-metastatic role of CASC15 in ovarian cancer in vivo, NOD/SCID mice were intraperitoneally injected with SKOV3 cells stably transfected with sh-CASC15 or sh-NC shRNA, and then to monitor metastasis, the mice were subjected to bioluminescent imaging on week 1, 3, and 5. Here, CASC15 is linked to ovarian cancer.