In diabetes-related disorders, ebselen improves glucose-stimulated insulin secretion in murine islets 20, shows beneficial effects on β-cell mass and function in a diabetic rat model 21 and attenuates hyperglycemia induced by either organo-phosphate diazinon in rats 22 or ischemia/reperfusion injury in gerbils 23. The gene discussed is INS; the disease is Hyperglycemia.