MAD2L2 and diabetic kidney disease: Although our previous studies have indicated the pathogenic effects of MAD2B on tubulointerstitial fibrosis, crescentic glomerulonephritis and podocyte injury 9, 23, 24, deeper understanding of biological functions of MAD2B in diabetic nephropathy is very limited and the precise mechanisms how MAD2B regulates podocyte injury remain to be elucidated.