SENP1 and metastatic malignant neoplasm in the lymph nodes: In addition, SENP1 expression was positively correlated with histologic grade (P = 0.045, χ2 = 6.918, r = 0.202) and lymph node metastasis (P = 0.023, χ2 = 9.564, r = 0.256) in TNBC specimens (Table 1).