VEGFA and neoplasm: VEGF expression in the tumors of the BI treatment group was reduced (control vs. BI: 19.09 ± 0.53 vs. 15.42 ± 1.30, p < 0.05), and the microvessel density (MVD) of CD34-labeled tumor tissue in the BI injection group was significantly lower than than that of the control group (control vs BI: 14.00 ± 1.00 vs. 5.00 ± 1.00, p < 0.001; Figure 2E).