VEGFA and plasma cell myeloma: Among the proangiogenic molecules, vascular endothelial growth factor (VEGF) plays an important role in maintaining angiogenesis; during the progression of myeloma, VEGFs trigger the angiogenic switch (Hong Wang et al., 2021; Zhiyao Wang et al., 2021) by stimulating vascular permeability and endothelial cell migration and proliferation.