The results of our study confirmed this hypothesis as we discovered that LIQ significantly inhibited Ang II-induced surface area increase of H9c2 cells and decreased the expression of cardiac hypertrophy markers ANP, BNP, and β-MHC mRNA in vitro by downregulating the ATE1 protein expression (Figures 2(a)–2(e) and 3(a) and 3(b)). The gene discussed is NPPA; the disease is cardiac hypertrophy.