However, none of the models, IL-17A alone (AUC: 0.553, p = 0.5596) or just Claudin-1 (AUC: 0.518, p = 0.8539) or their combination (AUC: 0.559, p = 0.5225), was shown to have better discriminatory performance to discriminate mild psoriasis from moderate-to-severe psoriasis (Supplementary Table 5 and Figure 3(c)). This evidence concerns the gene CLDN1 and psoriasis.