CRP levels < 80-100 mg/L (median 77 mg/L) are found in patients at low risk of progression (i.e., mild-moderate disease), whereas CRP levels > 180-200 mg/L (median 194 mg/L) are detected in patients with high rates of mortality (i.e., critical disease) (86, 87). This evidence concerns the gene CRP and glycogen storage disease VI.