Specifically, the upregulated components in tumor tissue were: glycoproteins latent-transforming growth factor beta-binding protein 1 (LTBP1) and latent-transforming growth factor beta-binding protein 2 (LTBP2), fibrillin-2 (FBN2), laminin subunit beta-3 (LAMB3), as well as ECM regulators lysyl oxidase (LOX) and ADAMTS-like protein 1 (ADAMTSL1). Here, FBN2 is linked to neoplasm.