Patients with POF presented higher values of white blood cells (P = 0.006), neutrophil (P = 0.002), NLR (P < 0.001), hematocrit (P = 0.003), triglyceride (P = 0.005), urea (P = 0.012), glucose (P = 0.001), and CRP (P < 0.001) at admission, and lower levels of lymphocyte (P = 0.006), calcium (P < 0.001), and albumin (P < 0.001). Here, ALB is linked to premature menopause.