It mainly acts on TNF, GAPDH, MAPK3, MAPK1, EGFR, CASP3, MAPK8, MTOR, IL-2, and MAPK14 and uses Kaposi sarcoma-related herpesvirus infection, AGE-RAGE signaling pathways in diabetic complications, pathways in cancer, apoptosis, hepatitis B, human cytomegalovirus signaling pathways such as infection, measles, and hepatitis C to treat pneumonia. This evidence concerns the gene TNF and cancer.