VM has the following characteristics: (1) there are no vascular endothelial cells on the inner wall of VM blood vessels; (2) tumor cells form vascular-like channels; (3) periodic acid Schiff (PAS) staining is positive and CD34 staining is negative, in contrast to the negative PAS staining and positive CD34 staining found in the endothelial vascular channel; and (4) plasma and RBCs are in the blood vessel-like channel [4, 5]. This evidence concerns the gene CD34 and neoplasm.