HER2是表皮生长因子受体(epidermal growth factor receptor, EGFR)酪氨酸激酶家族的重要成员。本文重点讨论针对HER2阳性NSCLC的两个ADCs药物,即Trastuzumab emtansine(T-DM1)和Trastuzumab deruxtecan(DS-8201a)。. Here, ERBB2 is linked to non-small cell lung carcinoma.