Interestingly, regardless of TAMs, tumor-infiltrating lymphocytes (TILs), or myeloid-derived suppressor cells (MDSCs) expressed β2-adrenergic receptors, cancer growth was slowed, and plasma immunosuppressive molecules were reduced after knockout of the MDSC ADRB2 gene in breast cancer transgenic mice [131]. The gene discussed is ADRB2; the disease is neoplasm.