DCX and Familial prostate cancer: Prostate cancer patients were divided into high-and low-risk groups, in which the density of DCX-positive cells was strongly associated with cancer invasion and recurrence, and DCX-positive progenitor cells initiated neurogenesis and could differentiate into adrenergic nerves, involved in the malignant progression of cancers, but the specific mechanisms about how to recruit cells and achieve differentiation is still a puzzle [37, 69].