In addition, our patient’s COVID-19-related inflammatory markers (fibrinogen, procalcitonin, and C-reactive protein) were remarkably high, and the onset of the ischemia during the third week was consistent with the period of hyperinflammation and cytokine storms, leading to a hypercoagulable state predisposing him to microvascular thrombosis, making the association between COVID-19 and his ischemic colitis more evident. This evidence concerns the gene CRP and deep vein thrombosis.