NRIR and colorectal carcinoma: Miao Yu et al. showed that exosomal FOXD2-AS1, NRIR and XLOC_009459 levels were significantly upregulated in 203 CRC patients and 80 early-stage CRC patients compared to 201 healthy individuals, possessing AUCs of 0.728, 0.660, and 0.682 for CRC [141].