TMPRSS11A and neoplasm: The recorded increase in the lifespan of EAC-bearing mice following the administration of Hesp, as well as the reduction in tumor growth responses and the decrease in the CEA level, were considered as valuable indications of the significant antitumor potency of Hesp recently demonstrated by Donia et al. [16] and Khedr and Khalil [50], which could be attributed to its ability to decrease the nutritional supplements and arresting the tumor growth [51].