Data from the present study, as above-described, show that the KCF18 peptide can achieve significant inhibitions of TNF-α, IL-1β, and IL-6 in endotoxemia mouse lung tissues, whereas the SEM18 peptide can achieve significant inhibitions of TNF-α and IL-1β, but not IL-6, in endotoxemia mouse lung tissues. Here, TNF is linked to serum lipopolysaccharide activity.