A number of pathways were downregulated after MOPV infection: ribosomes (at 6 and 24 h), TGFβ signaling, antigen processing/presentation, ubiquitin mediated proteolysis, TLR receptor signaling (Figure 2C), IFNα signaling (at 48 h), IL-6 JAK-STAT3 signaling, complement, IFNγ signaling, and TNFα signaling via NFκB (at 48 h for the last two) (Figure 2D). Here, IL6 is linked to infection.