Among the COVID-19 convalescent subjects, serum neutralizing activity at a 1:5 dilution significantly correlated with spike specific IgG and IgA levels in the HIV-1-infected subjects (HIV IgG: r2 = 0.758, p < 0.0001; HIV IgA: r2 = 0.431, p = 0.0005; Supplementary Figure S2b,c) and with spike specific IgG levels in the HIV-1-uninfected (HU IgG: r2 = 0.520, p = 0.002; HU IgA: r2 = 0.067, p = 0.332). Here, CD79A is linked to COVID-19.