The unique complex Corfu δ0β+ allele was first described in one of our patients from the Greek island of Corfu, who presented with non-transfusion dependent thalassemia at the age of 4 years with hemoglobin (Hb) of 9.2g/dL, comprising mainly HbF and low levels of HbA (5.8% with zero HbA2). This evidence concerns the gene HBA2 and thalassemia.