In this respect, we assessed the hematological phenotype of Corfu δ0β+ heterozygotes and compared it to β+-thalassemia heterozygotes with either the most common Greek variant (IVSI-110 G>A), which has similar severity to the IVSI-5 G>A β+ variant of the Corfu δ0β+ allele, or to heterozygotes with deletion type α0 thalassemia variants. The gene discussed is PPIB; the disease is thalassemia.