Moreover, the study and understanding of precise mechanisms of penetration/transport of cTns will increase their diagnostic value and validate new methods for diagnosing cardiovascular diseases through the use of other biological fluids; in particular, non-invasively obtained fluids, since their collection has a number of advantages (for example, painlessness and atraumatic nature, lower risk of introduction of blood-borne infections, and the possibility of obtaining biomaterial without the involvement of medical personnel) over the use of blood as a biomaterial. Here, CTNS is linked to cardiovascular disorder.