TFRC and infection: We also identify a subset of Sca-1+ CD71+ MHC-II+ myeloid cells in the ear dermis that is quite specific for mice infected with the non-healing LmSd strain, and we speculate that it represents a monocyte-derived subset that has upregulated Sca-1 expression in situ in response to infection, as we have previously observed that Leishmania infection alone was sufficient to promote Sca-1 expression in vitro [16].