Liu et al. also reported that mixing of acylated generation 5 PAMAM dendrimers with CXCR4 agonist, a long hydrophobic peptide (GGRSFFLLRRIQGCRFRNTVDD), enhanced its solubility and bioavailability, resulting in reduced lung metastasis in a breast cancer mouse model [27]. Here, CXCR4 is linked to breast carcinoma.