Some of them are active in the cytoplasm, including NF-κB-interacting lncRNA (NKILA), myocardial infarction-related transcription factors 2 (Mirt2), and HOX transcriptional antisense RNA (HOTAIR), while others regulate in the nucleus, such as Lethe, metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), and p50-associated cyclooxygenase-2 extragenic RNA (PACER) (Figure 3A). Here, MALAT1 is linked to myocardial infarction.