GPT and Hypoinsulinemia: In the current study, STZ resulted in significant hyperglycemia, hypoinsulinemia and significant proinflammatory cytokinin, in addition to antioxidant and oxidative stress with a noticeable upsurge in levels of TC, TG, LDL-C, amylase, ALT, AST and urea; meanwhile, HDL-C, total protein, albumin and liver glycogen markedly decreased.