An amount of 5 mg/kg ART significantly decreased the expression of p-Jak2/Jak2 and p-Stat3/Stat3 better than the 2.5 mg/kg treatment, suggesting that ART has therapeutic effects on lupus-prone MRL/lpr mice and involves Tfh cells and JAK–STAT signalling pathways [96]. Here, JAK2 is linked to systemic lupus erythematosus.