IHC staining by specific antibodies revealed that there was a decreased level of Ki-67-positive cells and an increased level of p27-positive cells in bladder tumor tissues from FKA-diet-fed mice compared to those from the control diet group (Figure 6A,B: 12.5 ± 2.3% and 35.2 ± 1.8% Ki-67-positive cells for FKA vs. control groups, p < 0.01; 55.9 ± 4.1 and 17.0 ± 3.4% p27-positive cells for FKA vs. control groups, p < 0.01). Here, MKI67 is linked to urinary bladder neoplasm.