Figure 4C,D demonstrates that dietary FKA decreased the incidence of hydronephrosis by an absolute decrease of 52% (from 72% (11/15) in the control group to 17% (1/6) in the FKA group) in male UPII-mutant Ha-ras transgenic mice and by 52% (from 60% (14/24) in the control group to 8% (2/25) in the FKA group) in female mice. The gene discussed is UPK2; the disease is hydronephrosis.