Furthermore, additional to the already studied cytokines, including IL-2, IL-8, IL-10, IL-13, nuclear factor kappa B, beta defensins, transforming growth factor beta 1, and cathelicidin LL37, altogether would explain their relationships in detailed interrelations by correlation analysis to substantiate the knowledge on the broad cytokine pleiad participating in both host immune defense and mastitis inflammation. The gene discussed is CXCL8; the disease is mastitis.