AKT1 and colorectal carcinoma: Quercetin inhibits in cell culture the activity of AKT (also known as protein kinase B) by hindering it from phosphorylation, thus decreasing the concentration of p-AKT, in several CRC representative cell lines, such as HT-29 [131,133], Caco-2 [132], DLD-1 [132], and HCT-15 [133].