Employing the expanded models and following adjustment for age, sex, race, poverty to income ratio, fasting blood glucose, systolic and diastolic blood pressure, HTN, DM, TG, HDL, and CRP the top quartile of total PUFA intake had a 21% lower likelihood of CKD (OR = 0.79 (0.68–0.88)). The gene discussed is CRP; the disease is diabetes mellitus.