INS and type 2 diabetes mellitus: Interestingly, at-home glucose-lowering drugs (metformin, dipeptidyl peptidase-4 inhibitors, insulin, sodium-glucose cotransporter 2 inhibitor, alone or in combination with metformin) prescribed for type 2 diabetes mellitus are not significantly associated with mortality or severe outcomes [50], but poor glucose control is associated with poor outcomes [70,71].