Recent findings highlight a “metabolic dialogue” in the tumour microenvironment between melanoma cells and adipocytes, based on the observation that the latter provide a local supply of FA, which are transferred to melanoma cells through the fatty acid transport protein 1 (FATP1)/sulute carrier family 27 (SLC27A) family of lipid transporters [233]. The gene discussed is SLC27A1; the disease is melanoma.