Some of the cytokines produced by human melanoma cells (IL-6, IL-8, CCL5 (RANTES), CXCL1–3 (MGSA-GROa-c), and monocyte chemotactic protein-1 (MCP-1/CCL2) are associated with tumour invasiveness and aggressiveness [123]. This evidence concerns the gene CXCL8 and neoplasm.