Because VCAM‐1 is expressed in large and small blood vessels after being stimulated by cytokines and it mediates the adhesion of lymphocytes, monocytes, eosinophils, and basophils to vascular endothelium, playing a role in signal transduction.32, 33 Lung specimens from patients with SSc and mainly cellular nonspecific interstitial pneumonia show increased VCAM‐1 expression.34 Here, VCAM1 is linked to systemic sclerosis.