In the present study, we became prosperous to announce 13 vDEGs whose expressional participation in colorectal cancer has not been previously declared, including 1) over-expressed ones (as possible oncogenes in colorectal cancer): MFAP2, CELSR3, and 2) under-expressed ones (as possible tumor suppressor genes in colorectal cancer): P2RY14, NPY1R, ARL14, TNXB, IGLV1-44, UGT2B15, IGHA2, IL1R2, PCK1, SOSTDC1, and UGT2A3. The gene discussed is IL1R2; the disease is colorectal cancer.