However, even for CVID,expert opinion varies as to which patients with decreased IgG and disturbed specificantibody responses should be classified under this diagnosis, some consideringcombination with decreased IgA or decreased IgM sufficient, andothers diagnosing CVID only in case IgA is decreased (± decreasedIgM) [12]. The gene discussed is CD79A; the disease is common variable immunodeficiency.