There were no differences when patients who went on to develop nosocomial infection during the trial treatment period were compared with those that did not (see Supplementary Figure 3a, http://links.lww.com/CTG/A783), nor any differences between paired sample analysis from days 1 and 5 in both the albumin treated and standard care patients (see Supplementary Figure S3b, http://links.lww.com/CTG/A783). Here, ALB is linked to nosocomial infection.