Recommended systemic treatments for patients with ATC are primarily taxanes, doxorubicin and platinum-based therapies for BRAF WT tumours, the dabrafenib/trametinib couplet for tumours with the BRAF V600E variant, and selective ALK, RET, or TRK inhibitors if an actionable fusion protein is identified (27, 28, 29). This evidence concerns the gene BRAF and neoplasm.