KDM5B and esophageal squamous cell carcinoma: By RT-qPCR and Western blot of normal human esophageal epithelial cells HET-1A and ESCC cell lines KYSE-150, ECA-109, TE-10, EC-9706, KDM5B was observed to be significantly overexpressed in all ESCC cell lines (Fig. 1E and F).