In the present study, cIMTmean and cIMTmax were predictors of mortality and thrombotic events in the univariate analysis; however, these associations were weak and no longer present after adjustment for potential confounders, which suggests that associations between cIMT and COVID-19 outcomes may be mediated by co-occurring risk factors such as obesity, existing cardiometabolic and pulmonary conditions, and CRP and D-dimer. This evidence concerns the gene CRP and obesity due to melanocortin 4 receptor deficiency.