APOE and atherosclerosis: When fed a regular diet, SR-B1/ApoE dKO mice display atherosclerosis in the aortic sinus and the mice possess lipid-rich coronary artery occlusions, myocardial fibrosis, and cardiac dysfunction (enlarged hearts, reduced ejection fraction and contractility, and abnormal echocardiography) at 4 ~ 5 weeks after birth.