MCM7 and nasopharyngeal carcinoma: To evaluate the effect of the circKIF18A-MCM7 axis on the cellular ROS level, we performed DCFH-DA staining and found that the circKIF18A-MCM7 axis showed no predominant effect on the DCFH-DA intensity in NPCs under oxidative stress (Fig. 6l, m), suggesting that the circKIF18A-MCM7 axis alleviates NPC degeneration without affecting the cellular ROS level and that the beneficial role of the circKIF18A-MCM7 axis can be attributed to suppression of senescence-related pathways in NPCs.