Acute leukemias in which the mixed lineage leukemia (MLL, also called MLL1 or KMT2A) gene is translocated at 11q23 accounts for approximately 35–50% of pediatric acute myeloid leukemia (AML) and up to 80% of acute lymphocytic leukemia (ALL). Here, KMT2A is linked to acute lymphoblastic leukemia.