IFNA2 and necrobiotic xanthogranuloma: Different treatments have been used for NXG with a wide variety of responses, such corticosteroids, IVIG, lenalidomide, cyclophosphamide, chlorambucil, thalidomide, melphalan, infliximab/rituximab, cladribine, bortezomib, vincristine, interferon alpha-2a, dapsone, ibarubicin, adalimumab, etretinate, cyclosporine, mycophenolate-mofetil, clofazimine, minocycline, doxycycline, acitretin, azathioprine and combined therapies (FCR, RCVP, vincristine/melphalane/cyclophosphamide/prednisolone).