CASP3 and non-small cell lung carcinoma: Herein, we demonstrated that CPX treatment led to the cleavage of both PARP and Caspase-3 (Fig. 5A) and induction of apoptosis (Fig. 5E) in NSCLC cells in a dose-dependent manner, while pretreatment of the NSCLC cells with NAC rescued the CPX-induced apoptosis (Fig. 5F).