Interestingly, miR-33a can inhibit NSCLC cell proliferation by downregulating METTL3 expression and its downstream genes, such as epidermal growth factor receptor (EGFR) and transcriptional coactivator with PDZ-binding motif (TAZ), via directly targeting the 3'UTR of METL3 mRNA [32]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.