BIRC5 and ovarian cancer: In contrast, a previous study comparing Survivin expression in ovarian cancer patients (n = 435) treated with platinum/cyclophosphamide (PC) (n = 244) or taxane/platinum (TP) (n = 191) found that patients with high nuclear Survivin expression and an accumulation of TP53 in tumor cells that were treated with TP had a decreased risk of recurrence and death [10].