NGFR and Abnormal retinal morphology: Although the use of zebrafish as a model to test the effects of therapeutic or neuroprotective compounds has been scarce until now (Cunvong et al., 2013; Saito et al., 2016), our results on NGF receptors’ expression and pathway activation in adult zebrafish strongly sustain the potential successful exploitation of zebrafish as a powerful alternative model for testing the efficacy of novel IV injection-based treatments for retinal diseases.