EZH2 and small cell lung carcinoma: Kim et al. [60] demonstrated that MELK phosphorylates the FOXM1 transcription factor and that EZH2 is targeted by the MELK/FOXM1 complex, which promotes CSC resistance to radiation, and that OTS167 (an inhibitor of MELK) effectively eliminates CSCs from small cell lung cancer (SCLC) [61].